Do people in the stolen thyroid cancer? What science speaks

In all sorts of ozompic and equal to the comparative of the body of the body, there are many challenges related to difficult or tall.

Between the fear of these fear and excess medications that GLPT-1 can cause another thyroid cancer. The risk is helping food and drugs have been required for the drug warnings To advise people who have the highest risk, such as those who have some other cancer history, to avoid using them.

The first GLP-1 (for 2 sugar) to hit the market 20 years ago. Having a large number of scholars, scientists study Thyroid cancers cause thyroid cancer- including study printed January last in JAMA Otolarypandalogy-head & neck.

All over the survey, as many but not all courses, not found additional risk in thyroid cancer associated with the use of GLP-1 diabetes). More than these events, the results can also give basic action because of why some lessons have found this such link.

Gizmodo spoke with the Author Rozna McCoy, Endocringist in University of Maryland, about the beginning of cancer of cancer-1s and thyroval. They discussed what they had found and products affected and began to use new medicines, even if they are miraculously heard. The next conversation that has been changed due to sounds and grammar.

Gizmodo: Why do the doctors have been worried about the threat of the thyrochian thyrochian thyrochian thyrochian thyro, Court of Ep-1 Cancer?

Rozilina McCoy: So when the medication is made, too. This test occurs in groups of animals, rats. In these early lessons, performed before they have been used, and the anxiety of cellists, the unique races of thyroid, are found in rats. And because this was seen in rats, where the first GLP-1 reaction, came with FDA warning that the drug should not be used for the people who have an anti-range of inflammatory, such as thyroid’s cancer.

Since then, there were a stress like this for people. Then for twenty years to the treatment of this class has been around, scientists expect to understand: Is this about people? And the challenges are that in medical trials, a flexible test that studies the drug, often registered several thousand patients. And perhaps because of a special type of thyroid covered, the risk that was not seen in the trials.

So the questions are always: Well, do these tests affect the most dangerous patients? Because again, since there is a black box of black box, trials will not be able to be in danger of risk, so they may be choosing dangerous people. Or do we see no cancer for this trials often become short? Most health problems are just a few years away, because it’s too expensive to do it. So don’t we follow patients long? Or is there no accident at all?

Examinations using the real world data requires confirmation of medical data to detect other events. What can we do if we look at what’s happening now as we have millions of people who are taking this medicine – can we see this sign?

Gizmodo: How different is your research to try to check this sign?

MCCY: We’re building up to the strong pit that’s already looking. But such lessons had some weaknesses, and there were some things we wanted to do about differently.

To one, we only use only information that can happen. So we have insurance for special insurance, for people who have the best Medicare insurance, about half the Medicarers, and for people who have traditional medicine. So we have people through the entire country with different insurance, various tensions, health care. We were able to combine about 400,000 patients, and almost 41,000 41,000 were helped by 11,000 adults, many adults use all types of drugs for GLP-1.

Tuesday is what we looked for thyroids of thyroids found from the first day and in, and looks directly one year, and then on. When we look at a few books who have already started, a great difference in the results that find a difference but others without getting the difference between cancer, which seemed to be what we did before. But some lessons did not look at least six earlier or one year, and they were a lesson that was not adding to risk, while the lesson they focused on the rest of the time, earns increases. So there was this question of: what’s going on here?

Gizmodo: Just explaining, one reason why this time requires this cancer out within six months to one year to one year to the treatment, isn’t it?

MCCY: Exactly, because the thyroid cancer usually takes a long time to make. Now there are, of course, brutal cancer that begins to grow faster. However, the fight against this is expected to harm patients and make people go to the hospital, to seek treatment, or death. And we know that it’s not going to happen because we have many books show that GLP-1S likes reduces the risk of dying.

Gizmodo: So which one is there?

MCCY: First, we have found that when we look at the full study period, no increase in the risk of cancer, which was good. However, when we look at the first year, we saw an increased risk. So that made us to look deeply for what would happen, what’s driving?

And we looked at the thyroid ultrasound, which is how to access this thyroid cancer. We saw patients who were starting on GLP-1, have the amount of ulaundo efficiency than other patients. And this is important because we know that there is a lot Increases thyroid cancer. We see the tumors or shines in the thickness in the thickness of the shields like cancer, why we call cancer. And if we couldn’t see them and did not remove the thyroid, the patient could be good. So this is very small, gentle, if not, growing cancer.

On returning to our research, I think of what we have found and that patients are found to be thyroids of treatment for medical services because they are finding ultrasound.

Gizmodo: Obviously lifters a question of why.

MCCY: I think maybe it is three times, even our data is not to tell us the direct statement that.

One thing that can happen is that patients can feel something in the neck that is concerned, as a cross, or maybe with the latest CTN. But if you are worried, there should be something in thyroid, and if you take a box warning, people can be more anxious and wanting to a lot.

Second, some doctors may worry about death 1 if they have no real evidence that there is nothing wrong with their thyroid. So there is a small promylactic causes to be convinced, especially if there is a family history of thyroid problems, so common, often with thyroid cancer.

And the third explanation means that when people lose the body taking a Serp-1, the reduction of the body is going to take place in the first few months of treatment. So people are thin, they can feel tinners on the test. In addition, combination with additional eyes, doctors can have a biopy and diagnose cancer.

The point of study is that we have shown Glp-1s bring up to more information for thyroid cancer. But they do not brush many thyroid cancer because I realize that the issue is a problem. And we know that the people who are taking-1s, that their The risk of dying and less More than patients are contributed to Sulfonylreas and DPP-4S (two other classes of diabetes).

Gizmodo: Obviously not the only learning look at the dangers and benefits of the group of drugs. For all, could you say that this calculation is resting right now? For the people who wrote them do have the dangers we know and want?

MCCY: How you claim to the question and how patients should think about it. And this is what I tell my patients always when we think if they start new medicines and the medicine must be. Because there’s always a product between the patient to be patient and what is possible? And calculations and specializes to each person in their own state, that is why it is important that the patients will be able to talk to their hospitals and understand the benefits and good benefits to them.

Therefore, we know that there is a great benefits depending on the influence of the heart disease, the risk of heart rate and damage is limited. People with a heart attack, few hospitals involved. People who are kidney diseaseThe amount of their illness is going to be delayed is delayed, and the amount of kidney growth and low. People who have overweight and reduces the body, the problems associated with a loss look good. Due to the diseases of hepatitis, arthritis, Sleep LupneaThey are well-behaved.

So to patients who may have heart disease, kidney diseases, or obesity, then the benefits of abdominal problems. We know that it would be difficult for nalerua, diarrhea, discharge. In the people who reduce the body faster, there is an increased risk of gallstones, as you can have any kind of small body. If people lose weight without exercising, then they lose a lot of muscles, so that they can get too weak.

So the secret is: Will you benefit? And you’re damaged? And your threat can pass the change in life, such as the gym not to have nausea, to take out, or small foods or less foods. So there are always the products. If I have a sick patient who has the worst effects, then the benefits may not be advantageous because they are sad. But if they are willing to, I think they are. It’s the idea of ​​every sick person.